The first analyses of TIGER focused on a set of key co-morbidities frequently reported by tinnitus patients: temporo-mandibular joint (TMJ) disorders, headaches and hyperacusis. In 3 sequential studies, TIGER shows the lack of sex-influences in their association with tinnitus. Thanks to a deep phenotyping strategy, TIGER proposes that the mechanisms underlying tinnitus with hyperacusis are distinct from those associating tinnitus with TMJ or headache.
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